Harvesting Benefits from Cannabinoids

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Harvesting Benefits from Cannabinoids

With the ongoing liberalization of cannabis laws in many parts of the United States that are decriminalizing its recreational and/or medical use, there is much discussion about the benefits of cannabinoids and how to mitigate potential negative societal repercussions of increased access to them. At risk of being overshadowed amidst this debate is the fascinating biology coming to light about ho...

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Cannabinoids.

Since the discovery of an endogenous cannabinoid system, research into the pharmacology and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein coupled cannabinoid receptors, CB(1) and CB(1), have been cloned and several putative endogenous ligands (endocannabinoids) have been detected during the past 15 years. The main endocannabinoids are arachidonoyl ethan...

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Cannabis sativa L. is one of the oldest plants known in medicine and one that has been most studied with respect to its phytochemistry (Turner et al., 1980). Currently, a total of 483 constituents have been identified in cannabis of which 66 are cannabinoids (Ross et al., 1995). About 20 flavonoids have been reported to be present in the cannabis plant as aglycones or as conjugated O-glycosides...

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Background-Cannabis is the most popular illicit drug in the Western world. Repeated cannabis use has been associated with short and long-term range of adverse effects. Recently, new types of designer-drugs containing synthetic cannabinoids have been widespread. These synthetic cannabinoid drugs are associated with undesired adverse effects similar to those seen with cannabis use, yet, in more s...

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ژورنال

عنوان ژورنال: Cell

سال: 2016

ISSN: 0092-8674

DOI: 10.1016/j.cell.2016.12.001